508 research outputs found

    Bayesian decision making in human collectives with binary choices

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    Here we focus on the description of the mechanisms behind the process of information aggregation and decision making, a basic step to understand emergent phenomena in society, such as trends, information spreading or the wisdom of crowds. In many situations, agents choose between discrete options. We analyze experimental data on binary opinion choices in humans. The data consists of two separate experiments in which humans answer questions with a binary response, where one is correct and the other is incorrect. The questions are answered without and with information on the answers of some previous participants. We find that a Bayesian approach captures the probability of choosing one of the answers. The influence of peers is uncorrelated with the difficulty of the question. The data is inconsistent with Weber's law, which states that the probability of choosing an option depends on the proportion of previous answers choosing that option and not on the total number of those answers. Last, the present Bayesian model fits reasonably well to the data as compared to some other previously proposed functions although the latter sometime perform slightly better than the Bayesian model. The asset of the present model is the simplicity and mechanistic explanation of the behavior.Comment: 8 pages, 6 figures, 1 tabl

    Dynamics of link states in complex networks: The case of a majority rule

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    Motivated by the idea that some characteristics are specific to the relations between individuals and not of the individuals themselves, we study a prototype model for the dynamics of the states of the links in a fixed network of interacting units. Each link in the network can be in one of two equivalent states. A majority link-dynamics rule is implemented, so that in each dynamical step the state of a randomly chosen link is updated to the state of the majority of neighboring links. Nodes can be characterized by a link heterogeneity index, giving a measure of the likelihood of a node to have a link in one of the two states. We consider this link-dynamics model on fully connected networks, square lattices and Erd \"os-Renyi random networks. In each case we find and characterize a number of nontrivial asymptotic configurations, as well as some of the mechanisms leading to them and the time evolution of the link heterogeneity index distribution. For a fully connected network and random networks there is a broad distribution of possible asymptotic configurations. Most asymptotic configurations that result from link-dynamics have no counterpart under traditional node dynamics in the same topologies.Comment: 9 pages, 13 figure

    Is the Voter Model a model for voters?

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    The voter model has been studied extensively as a paradigmatic opinion dynamics' model. However, its ability for modeling real opinion dynamics has not been addressed. We introduce a noisy voter model (accounting for social influence) with agents' recurrent mobility (as a proxy for social context), where the spatial and population diversity are taken as inputs to the model. We show that the dynamics can be described as a noisy diffusive process that contains the proper anysotropic coupling topology given by population and mobility heterogeneity. The model captures statistical features of the US presidential elections as the stationary vote-share fluctuations across counties, and the long-range spatial correlations that decay logarithmically with the distance. Furthermore, it recovers the behavior of these properties when a real-space renormalization is performed by coarse-graining the geographical scale from county level through congressional districts and up to states. Finally, we analyze the role of the mobility range and the randomness in decision making which are consistent with the empirical observations.Comment: 13 pages, 13 figure

    Cell death in hepatocellular carcinoma: Pathogenesis and therapeutic opportunities

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    Hepatocellular carcinoma (HCC) is the most prevalent primary liver cancer and the third leading cause of cancer death worldwide. Closely associated with liver inflammation and fibrosis, hepatocyte cell death is a common trigger for acute and chronic liver disease arising from different etiologies, including viral hepatitis, alcohol abuse, and fatty liver. In this review, we discuss the con-tribution of different types of cell death, including apoptosis, necroptosis, pyroptosis, or autophagy, to the progression of liver disease and the development of HCC. Interestingly, inflammasomes have recently emerged as pivotal innate sensors with a highly pathogenic role in various liver diseases. In this regard, an increased inflammatory response would act as a key element promoting a pro-oncogenic microenvironment that may result not only in tumor growth, but also in the formation of a premetastatic niche. Importantly, nonparenchymal hepatic cells, such as liver sinusoidal endothelial cells, hepatic stellate cells, and hepatic macrophages, play an important role in establishing the tumor microenvironment, stimulating tumorigenesis by paracrine communication through cytokines and/or angiocrine factors. Finally, we update the potential therapeutic options to inhibit tumorige-nesis, and we propose different mechanisms to consider in the tumor microenvironment field for HCC resolution. © 2021 by the authors. Licensee MDPI, Basel, Switzerland

    Handlebar injury in children: Are we ignoring the signs?

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    AbstractThe diagnosis of blunt intestinal injury in children is difficult and often delayed. We describe two cases of delayed diagnosis of intestinal injury following handlebar injury with abdominal wall tattooing. We review the literature to try and determine the usefulness of handlebar tattooing characteristics as a clinical sign for underlying small bowel injury in order to reduce delayed treatment. We propose a management algorithm for patients with handlebar tattooing

    Laser transmission welding of Acrylonitrile-Butadiene-Styrene (ABS) using a tailored high power diode-laser optical fiber coupled system

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    Laser transmission welding (LTW) of polymers is a direct bonding technique which is already used in different industrial applications sectors such as automobile, microfluidic, electronic and biomedicine. This technique offers several advantages over conventional methods, especially when a local deposition of energy and minimum thermal distortions are required. In LTW one of the polymeric materials needs to be transparent to the laser wavelength and the second part needs to be designed to be absorbed in IR spectrum. This report presents a study of laser weldability of ABS (acrylonitrile/butadiene/styrene) filled with two different concentrations of carbon nanotubes (0.01% and 0.05% CNTs). These additives are used as infrared absorbing components in the laser welding process, affecting the thermal and optical properties of the material and, hence, the final quality of the weld seam. A tailored laser system has been designed to obtain high quality weld seams with widths between 0.4 and 1.0mm. It consists of two diode laser bars (50W per bar) coupled into an optical fiber using a non-imaging solution: equalization of the beam quality factor (M2 ) in the slow and fast axes by a pair of micro step-mirrors. The beam quality factor has been analyzed at different laser powers with the aim to guarantee a coupling efficiency to the multimode optical fiber. The power scaling is carried out by means of multiplexing polarization technique. The analysis of energy balance and beam quality is performed in two linked steps: first by means ray tracing simulations (ZEMAX® ) and second, by validation. Quality of the weld seams is analyzed in terms of the process parameters (welding speed, laser power and clamping pressure) by visual and optical microscope inspections. The optimum laser power range for three different welding speeds is determinate meanwhile the clamping pressure is held constant. Additionally, the corresponding mechanical shear tests were carried out to analyze the mechanical properties of the weld seams. This work provides a detailed study concerning the effect of the material microstructure and laser beam quality on the final weld formation and surface integrity

    Bilateral anterior ischemic optic neuropathy after bilateral neck dissection

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    María J Suárez-Fernández, Antonio Clariana-Martín, Enrique Mencía-Gutiérrez, Esperanza Gutiérrez-Díaz, Teresa Gracia-García-MiguelOphthalmology Department, 12 de Octubre Hospital, Complutense University, Madrid, SpainPurpose: The risk of visual loss after nonocular surgeries is very low, between 0.2% and 4.5%. According to the American Society of Anesthesiologists, ischemic optic neuropathy has been reported mostly after spinal surgery (54.2%), followed by cardiac surgery and radical neck dissection (13.3%). It may occur in association with some conditions that include systemic hypotension, acute blood loss and hypovolemia.Case report: A 46-year-old woman, whose diagnosis was laryngeal squamous cell carcinoma, complained of visual loss in her right eye two days after surgery (laryngectomy with bilateral radical neck dissection and left jugular ligature) and one day later in her left eye. The diagnosis was nonarteritic anterior ischemic optic neuropathy.Conclusion: Anterior ischemic optic neuropathy related to nonocular surgery is usually bilateral and its prognosis is very poor, resulting in blindness or severe visual loss. Although rare, patients should be warned about this complication, which has a profound impact on quality of life, since no therapeutic measure, including correction of hypotension and anemia, seems to improve the prognosis of this complication.Keywords: ischemic optic neuropathy, visual loss, radical neck dissection, blood los

    Bimanual robot control for surface treatment tasks

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    This is an Author's Accepted Manuscript of an article published in Alberto García, J. Ernesto Solanes, Luis Gracia, Pau Muñoz-Benavent, Vicent Girbés-Juan & Josep Tornero (2022) Bimanual robot control for surface treatment tasks, International Journal of Systems Science, 53:1, 74-107, DOI: 10.1080/00207721.2021.1938279 [copyright Taylor & Francis], available online at: http://www.tandfonline.com/10.1080/00207721.2021.1938279[EN] This work develops a method to perform surface treatment tasks using a bimanual robotic system, i.e. two robot arms cooperatively performing the task. In particular, one robot arm holds the work-piece while the other robot arm has the treatment tool attached to its end-effector. Moreover, the human user teleoperates all the six coordinates of the former robot arm and two coordinates of the latter robot arm, i.e. the teleoperator can move the treatment tool on the plane given by the work- piece surface. Furthermore, a force sensor attached to the treatment tool is used to automatically attain the desired pressure between the tool and the workpiece and to automatically keep the tool orientation orthogonal to the workpiece surface. In addition, to assist the human user during the teleoperation, several constraints are defined for both robot arms in order to avoid exceeding the allowed workspace, e.g. to avoid collisions with other objects in the environment. The theory used in this work to develop the bimanual robot control relies on sliding mode control and task prioritisation. Finally, the feasibility and effectiveness of the method are shown through experimental results using two robot arms.This work was supported by Generalitat Valenciana [grant numbers ACIF/2019/007 and GV/2021/181] and Spanish Ministry of Science and Innovation [grant number PID2020117421RB-C21].García-Fernández, A.; Solanes, JE.; Gracia Calandin, LI.; Muñoz-Benavent, P.; Girbés-Juan, V.; Tornero, J. (2022). Bimanual robot control for surface treatment tasks. International Journal of Systems Science. 53(1):74-107. https://doi.org/10.1080/00207721.2021.19382797410753

    Physical activity and leisure habits and relation with Ruffier index in adolescents

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    El objetivo del estudio fue medir y correlacionar la práctica de actividad física y con el Índice de Ruffier (IR) en adolescentes. A un total de 884 alumnos (edad=16,4±0,8 años) se les midió la actividad física con la Versión modificada del Assessment of Physical Activity Level Questionnaire (APALQ) y se evaluó la capacidad de adaptación al esfuerzo mediante el Test Ruffier. La media del Índice de Ruffier fue 11,1±4,6 y el Índice de actividad física (IAF) 13,8±4,4. Las relaciones entre IAF y el IR, y entre horas de ocio sedentario e IR resultaron ser significativas aunque débiles (r=-0,31; p=0,000). En el IR los chicos presentaron valores superiores (t= -8,78; p= 0,000) a las chicas. También destinan más tiempo a la práctica de AF y estas diferencias fueron significativas en AF reglada y no reglada y en participación en competición (p=0,000), mientras que las chicas destinan más tiempo a actividades sedentarias como leer y estudiar (p=0,000). Es necesario promover la práctica de actividades físico-deportivas, especialmente entre las chicasThe aim of the study was to assess and correlate physical activity practice and fitness level in adolescents. A total of 884 students (age=16,4±0,8 years) answered the modified version of the “Assessment of Physical Activity Level Questionnaire (APALQ)” and aerobic capacity was assessed through the Ruffier Test. The mean Ruffier Index (IR) was 11,1±4,6 and the mean Physical Activity Index (IAF) was 13,8±4,4. The relationship between IAF and IR, and between sedentary activities in leisure time and IR, was significant (r=-0,31; p=0,000). although weak. Boys showed higher physical fitness values (t= -8,78; p= 0,000) and spent more time practicing physical activity. These differences were significant for both regulated and not regulated physical activity and for participation in competition (p=0.000). Girls spent more time in sedentary activities like reading and studying (p=0.000). It is necessary to promote physical activity and sport practice, especially among girls

    Non-localized postactivation performance enhancement (PAPE) effect in trained athletes: a pilot study

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    Fifteen trained athletes were assessed for postactivation performance enhancement (PAPE) of squat jumps (SJ) and power push-ups (PPU) following upper body activation, lower body activation, upper and lower body activation, and rest. SJ improved similarly across all four conditions. PPU could not be assessed. Since the protocol of SJ and PPU involved upper and lower body activation and caused PAPE in SJ, future work is required to determine if a non-localized PAPE effect exists.CTS-527: Actividad física y deportiva en el medio acuátic
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